1, treatment of non-gonococcal urethritis main application of drugs (1) to chlamydia and mycoplasma co-sensitive drugs are tetracycline, dimethylamino tetracycline, doxycycline, sparfloxacin, fluazinic acid, clarithromycin, azithromycin. (2) Chlamydial infection during pregnancy doxycycline, tetracycline, sparfloxacin, fluazinic acid, is prohibited in pregnant women, sulfadimethoxazole is prohibited in women in late pregnancy or lactation, erythromycin is available, the latest data suggest that azithromycin may be safe and effective. 2, treatment options: choose drugs that are effective against both chlamydia and mycoplasma: (1) urethritis (mucous cervicitis): doxycycline 100mg orally twice daily for 7-14 days; or azithromycin 1.0g single dose orally, half-life up to 60h, can maintain effective concentration for 5 days; or fluazinic acid 0.2g orally twice daily for 7 -or 0.3g of roxithromycin orally once a day for 7 days, or 0.15g orally twice a day for 7 days. (2) Pregnant women: Erythromycin 500mg orally 4 times daily for 7 days; or Erythromycin 250mg orally 4 times daily for 14 days. (3) Neonatal conjunctivitis or neonatal pneumonia: both erythromycin 50mg/kg daily in 4 oral doses for 10-14 days. (4) Those with co-infection of HIV: the same treatment as for patients with HIV.