Acute poisoning by barium is most often caused by accidental ingestion, and gastric acid promotes the dissolution of certain barium compounds. Barium has a small amount of deposition in various organs, with the highest content in bone. In the early stage of barium chloride poisoning, there are symptoms of gastrointestinal irritation such as nausea, vomiting, diarrhea and abdominal pain. Later on, paralysis may also occur, with facial bruising, chilling of the limbs, cold sweating, muscle tremor, convulsions, paralysis of the tongue muscles and throat and speech disorders. Dyspnea, vertigo, tinnitus, and visual disturbances may also be seen. Poisoned patients are usually conscious. The absorption of soluble barium salt is rapid, the development of poisoning symptoms is fast, and can be seen to have elevated blood pressure, decreased blood potassium, cardiac rhythm disorders and other toxic myocardial damage. Chronic poisoning, manifestations of extreme weakness, dyspnea, salivation, oral mucus inflammation, ocular colitis, dyspeptic diarrhea, gastric hemorrhage, cardiac arrhythmia, tachycardia, elevated blood pressure, urinary disorders. Sometimes there is also loss of hair and eyebrows. Frequent exposure to barite (BaSO4) dust may cause “pneumoconiosis”.