Renal cortical necrosis is the result of obstruction of the small arteries of the renal cortex due to various diseases. Other causes include rejection of the transplanted kidney, burns, inflammation of the pancreas (pancreatitis), injuries, snake bites, and poisoning. Examples include phosphorus and arsenic poisoning. One of the advances in the dietary treatment of uremia in the last decade is the need to further reduce protein intake with the addition of essential amino acid preparations when renal deterioration can no longer maintain adequate urea nitrogen levels on a high biomass low protein diet alone. Commonly used dosage forms include powders, tablets, syrups, etc., which can also be supplied intravenously. The powder can be eaten with wheat and corn starch to make various kinds of snacks. Renal cortical necrosis Patients with chronic renal insufficiency have a low percentage of plasma essential amino acids and a high percentage of non-essential amino acids. Some scholars have found that the above diet is well utilized and nitrogen balance is easily obtained. It has been suggested that oral essential amino acids promote hepatic protein synthesis and intravenous administration promotes intramuscular synthesis. With essential amino acids, protein intake is lower than that of high biomass low protein diet, which can meet the need of essential amino acids in the body, easily obtain nitrogen balance, and reduce nitrogen metabolites; meanwhile, phosphorus intake can be reduced, so it can reduce the damage of calcium deposition to renal units. In addition, the choice of protein is not limited to high biomass protein, which is conducive to regulating the patient’s taste and making it more acceptable to the patient. The supply of caloric energy must be adequate in low protein (30-50 g/day) diets. The ratio between caloric energy and nitrogen supply should preferably be 300-450 kcal:1 g. The minimum daily intake of caloric energy is 35 kcal/kg body weight. About 2000-2500 kcal per day. Sodium and potassium If combined with edema and hypertension (diastolic blood pressure greater than 110 mmHg), sodium should be limited to 40 mg equivalent/day (920 mg/day) is more appropriate (equivalent to a salt-free diet). If the patient is taking diuretics or has vomiting or diarrhea, sodium should no longer be restricted and should even be supplemented. If the patient is combined with hyperkalemia, the intake should be less than 40 to 60 milliequivalents (1560 to 2340 mg) per day. If the daily urine output is greater than 1000 ml and the blood potassium level is normal, there is no need to restrict potassium intake. The potassium-restricted diet should avoid fruit juices and carefully choose vegetables and fruits. If the patient’s daily urine output increases to more than 1500 ml, the potassium level should be monitored and supplemented if it is too low. Calcium and phosphorus, magnesium When the glomerular filtration rate drops to 40-50 ml/min, the excretion of phosphorus filtration is reduced, leading to an increase in blood phosphorus. If renal function deteriorates further, the elevation of blood phosphorus cannot be controlled, high blood scales and damage to the renal parenchyma diminish the kidney’s ability to synthesize active vitamin D. The blood calcium concentration decreases, inducing osteoporosis. The ideal therapeutic diet should increase the calcium content and decrease the phosphorus content. Foods rich in calcium include milk, green leafy vegetables, sesame paste, etc. However, sometimes it is difficult to achieve the desired goal due to the complexity of the disease, the clinical practice is usually adjusted with pharmaceutical preparations as a rule. For example, in adults, when the glomerular filtration rate (GFR) is 20-25 ml/min, the patient is given 1 to 2 grams of oral calcium (such as calcium carbonate, calcium lactate or sodium citrate) daily. To reduce intestinal phosphorus absorption, patients are given oral aluminum hydroxide or aluminum carbonate latex to combine with phosphorus for excretion. The standard for mastering phosphorus intake in the diet is that when the patient’s glomerular filtration rate (GFR) is less than 25 ml/min, the daily phosphorus content of the diet should be 45 to 52 milli-equivalents (700 to 800 mg). Aluminum hydroxide latex should also not be discontinued. Chronic renal failure patients due to long-term diet restriction or secondary hyperparathyroidism, also inhibit the absorption of magnesium, when magnesium may be in equilibrium. But when the patient urinates little, if there is a large amount of magnesium load is difficult to excrete, the body excess magnesium may produce high blood magnesium, then should limit the intake. Fluid and water balance It is important for patients to master the balance of fluid intake and output. Generally depending on the amount of excretion to determine the intake. Excretion all day includes urine, respiratory and skin evaporation and digestive fluid. Generally, the daily water loss through the skin and respiration is about 700 to 1000 ml, while food entering the body through metabolism can also produce some water about 300 to 400 ml per day, and the total water loss in addition to urine excretion is about 500 ml per day. Renal cortical necrosis Therefore, the patient’s daily fluid intake can be added to the previous day’s urine volume plus about 500 ml of water as a reference for replenishment. However, when the patient has fever, vomiting, diarrhea and other symptoms, more fluids should be added. When the overall condition is in remission, the amount of fluid intake can be around 1200 ml per day. Vitamin supplementation The level of water-soluble vitamins in the patient’s body will decrease due to abnormal metabolism and insufficient nutritional intake, and the synthesis of active vitamin D will be affected by abnormal calcium and phosphorus metabolism. Carbohydrates and fats About 40% to 60% of patients with chronic renal failure have type IV hyperlipidemia (sugar-induced hypertriglyceridemia), which is not only caused by endogenous factors, but also related to the high proportion of carbohydrates and fats in the treatment diet. Atherosclerosis is induced due to disorders of fat metabolism. Therefore, attention should be paid to the ratio of unsaturated to saturated fatty acids (P/S) in the fat supply. Some scholars believe that under a certain calorie supply, P/S value of 1:1.5 is better. In order to use vegetarian oil is appropriate. In conclusion, the diet for chronic renal failure should be low salt, low protein, high calorie, appropriate micronutrient and vitamin diet, and then with Chinese medicine treatment can delay the process of renal failure, which can reduce or delay the time of hemodialysis for renal failure.