Renal cortical necrosis is a rare form of kidney tissue death that affects only part or all of the outer layer (cortex) of the kidney and not the inner layer (medulla). Renal cortical necrosis can occur at any age. About 10% of cases occur in infants and children. More than half of newborns with cortical necrosis are delivered with abrupt placental separation (placental abruption); the other most common cause is bacterial infection of the blood stream (sepsis). In children, cortical necrosis can be followed by infection, dehydration, shock, or hemolytic uremic syndrome. In adults, bacterial sepsis causes cortical necrosis in about 1/3 of all cases. Prevention of renal cortical necrosis: hydrate to prevent kidney failure, pay attention to changes in urine, have regular medical checkups to prevent hereditary kidney disease, eat a light diet and avoid excessive use of supplements, and reduce the proportion of fats and oils in food, as too much fats and oils can cause hypertension and vascular sclerosis, which are also harmful to the kidneys. It is also pointed out in many related studies that the limitation of protein intake and control of high blood lipids are effective methods to prevent the deterioration of kidney disease.