Corneal neovascularization to a certain extent can severely affect vision or even blindness. If the early vascular network is in the peripheral part of the cornea, it will not seriously affect vision; however, if the primary disease of the cornea is not eradicated, it may lead to a significant proliferation of vascular tissue throughout the cornea, which can seriously affect vision. It is not only the corneal neovascularization that causes severe vision loss in clinical practice, but some primary pathologies, such as infected lesions of the cornea, are also major causes of vision loss. In severe cases, corneal neovascularization can lead to blindness. The normal corneal tissue is completely transparent, but after dense corneal neovascularization, the corneal transparency decreases, resulting in the inability of external light to enter the eye.