Hepatitis B DNA 3.43E+03 usually indicates positive hepatitis B virus, whether it is serious or not should depend on the situation. Patients are advised to undergo abdominal ultrasound, liver function and other related examinations. If the liver function is normal, it is relatively not serious, and it mostly indicates that the patient is a carrier of hepatitis B virus, so there is no need for antiviral treatment in clinical practice, and regular review is required, but attention should be paid to avoid transmission to others through blood and sex. If the liver function is abnormal, the patient is more likely to be a hepatitis B patient and needs to be treated under the guidance of a doctor in a timely manner. The treatment of hepatitis B is usually based on medication, commonly used drugs include antiviral drugs such as entecavir, tenofovir, etc., and liver protection drugs such as glycopyrrolate preparations. In addition, it is recommended that hepatitis B virus carriers and patients should develop good habits in daily life, ensure sufficient sleep, avoid overwork, avoid smoking and alcohol and other bad habits, and maintain a good state of mind, which is conducive to recovery. At the same time, strictly follow the doctor’s prescriptions for medication, regular review so that the doctor can adjust the treatment plan in a timely manner, and if abnormalities occur, you should respond to the doctor in a timely manner.