In perimenopausal women, the endometrium is sometimes thickened by ultrasound because of irregular menstruation. Once this happens, the general principle of treatment is as follows: if the woman does not have a period for a long time, she can use some treatment under the guidance of a specialist, such as oral medication, especially progesterone preparations, so that the endometrium can be transformed once, generally the transformation time, that is, the time to take the medication, about 10-15 days, there will be a withdrawal bleeding after stopping the medication, after bleeding if the endometrium becomes thinner, it is safe. After the bleeding, if the endometrium becomes thinner, there is no problem and it is safer. However, if this does not work and the endometrium is still thickened after bleeding, and there is even an irregular rebound, it is best to have some tests performed by a specialist, such as hysteroscopy or diagnostic endometrial scraping, and minimally invasive endometrial biopsy can be done to rule out the risk that the thickened endometrium is an endometrial lesion, and these should be done These should be done.