Photodynamic therapy is a new technology for skin treatment that originated in Europe. It is a new means of disease treatment based on the interaction of light, photosensitizers and oxygen. It is now widely used in the field of skin aesthetics for the treatment of acne. Local treatment with photodynamic therapy, the photodynamic reaction generated in the aerobic skin environment will act on sebaceous glands and related damaged skin cells, which will have a significant effect on acne and hyperplastic pustular acne skin, and effectively prevent the production of acne scarring. At the same time, it can improve the sebum secretion on the surface of the skin and restore the skin to a healthy state with a natural luster and beauty. Photodynamic therapy for acne is fast-acting, effective, long-lasting, simple and safe, and is the first choice for patients with moderate to severe acne who are not well treated by traditional methods.