1, non-ergot dopamine agonists: pramipexole 0.25-0.75mg/day can significantly reduce the symptoms of restless legs syndrome and improve sleep. Can have nausea, drowsiness and other mild side effects. 2, dopamine drugs: Medroba from a small dose of 125mg, 2 times / day, gradually and slowly increase the dose. However, with the prolongation of the drug can be seen to worsen the symptoms or reduce the efficacy. 3, anti-epileptic drugs: gabapentin treatment dose of 200mg to 2000mg, rare serious adverse reactions include dizziness, drowsiness and peripheral edema. 4, sedation: clonazepam Treatment dose 0.5 ~ 1mg, it has a long half-life, can cause daytime sleepiness, sluggishness and balance disorders, especially in the elderly. Excessive sedation or pathological drug dependence should be observed.