1.Single solid nodule more than 1 cm in size. 2.Single solid nodule less than 1 cm but with calcification or abnormal blood flow or lymph node enlargement. 3.Single cyst more than 2-3 cm in size. 4.Multiple nodules in which the largest nodule is more than 2 cm or nodules with calcification or abnormal blood flow or lymph node enlargement. 5, Thyroid nodule with previous history of neck radiation exposure or treatment. 6, Age less than 20 years old or greater than 70 years old. 7, Male patients with thyroid nodules. 8.Patients with retrosternal thyroid enlargement. 9.Patients with sudden increase in thyroid nodules recently. 10, Thyroid nodules with pressure, voice changes, swallowing difficulties and irritating cough. There are many patients with thyroid nodules, and patients hear about various treatments, but patients are most concerned about those cases that require surgery. I will now discuss my own views on the indications for surgery of thyroid nodules. There are many diseases that can cause thyroid nodules, including nodular goiter, adenoma, subxiphoiditis, Hashimoto’s disease, hyperthyroidism, and thyroid cancer. Among them, adenoma and thyroid cancer are absolute indications for surgery, while the other nodules, thyroiditis and hyperthyroidism are relative indications for surgery. Which of these relative indications require active surgery, which can be treated medically, and which can be monitored? This is determined on a disease-by-disease basis. If the above-mentioned diseases are combined with tracheal compression, if the mass is huge and affects life, if the mass grows upward in the mediastinum, if the nodule is suspected to be malignant or has become malignant, or if the hyperthyroidism cannot be treated with radioactive iodine for other reasons, active surgery should be performed. Among the above cases, nodules suspected of malignancy or already malignant are the most difficult to determine in clinical work. Even if experienced doctors combine imaging and laboratory tests, the correct diagnosis rate is about 80%. The other 20% depends on the patient’s attitude towards the disease. If the patient is very afraid of the disease and it affects his work and life, he should be operated to relieve the physical and mental impact on the patient, if the patient is calm, he can be observed and the treatment method will be decided after a clear diagnosis. For patients who can be clearly diagnosed as benign nodules, as long as there is no pressure and it does not affect their work life, they can be treated non-operatively or under observation.