Lung cancer mainly includes lung adenocarcinoma, lung squamous carcinoma and small cell lung cancer, among which lung squamous carcinoma and lung adenocarcinoma can be unified as non-small cell lung cancer. Advanced lung cancer requires comprehensive treatment, i.e., combined chemotherapy, radiotherapy, targeted therapy and immunotherapy, and the treatment methods vary according to the pathological types of lung cancer, as follows: 1. Advanced non-small cell lung cancer: patients should prefer molecular targeted therapy if they have driver gene mutation, and if there is no driver gene mutation and PD-L1 expression >50%, first-line K-drug monotherapy can be chosen Immunotherapy, if PD-L1 expression is weakly positive between 0-50%, chemotherapy combined with K-drug immunotherapy combined regimen can be chosen, the effect is generally better than chemotherapy alone, for lung cancer patients after the progression of first-line chemotherapy, second-line immunotherapy, whether K-drug or O-drug efficacy, is better than chemotherapy alone. 2, advanced small cell lung cancer: treatment may still be mainly chemotherapy, but also according to special circumstances, combined with radiotherapy. The latest research shows that the combination of immunotherapy at this stage is also better than chemotherapy or radiotherapy alone.