In the past year, I have performed more than 50 cases of secondary surgery for recurrent glioma, and I have the following experience to share with patients and families. When glioma is treated for the first time, the family is not psychologically prepared and does not have an accurate understanding of glioma, so surgery is almost an inevitable choice. A few months or years after the first surgery, when the inevitability of malignant glioma recurrence is gradually accepted and better understood, the next step of treatment becomes a difficult decision when faced with glioma recurrence. On the one hand, there is the heartfelt reluctance for the loved ones, on the other hand, there is the coldness of glioma, and probably the economic pressure, it is really difficult to choose. Giving up treatment is painful, and continuing treatment is still painful. In my personal opinion, the first surgery for glioma is to protect the neurological function in the first place and to prolong the life of the patient in the second place; the second surgery for recurrent glioma is to prolong the life of the patient in the first place and to protect the neurological function in the second place. Therefore, I spend the most time with the families of patients with recurrent glioma in each clinic, because I know how difficult it is. It is these respectful families who inspire me and motivate me to perform these difficult surgeries. I make sure that the families have an accurate understanding of glioma, a strong commitment to it, and a full understanding of my treatment philosophy. Secondary surgery is indeed many times more difficult than primary surgery because of adhesions, because of structural disorders, because of cerebral edema after radiation therapy, and so on. I remember a colleague saying that he would rather do 10 primary surgeries than 1 secondary surgery. Whenever I encountered difficulties, those expectant eyes were the motivation for me to persist in my pursuit of perfection. Almost all of these secondary surgical cases achieved the expected results, with total or subtotal tumor resection, removal of bone flaps, adequate decompression, and opening of cerebrospinal fluid circulation, with some loss of function, but most of them were still preserved, and the families were satisfied. At the time of discharge, I explained again and again that companionship is more important than treatment! Walk and talk more with the patient, get some sunshine, prolong as long as you can, keep your head down and work hard every step of the way, and don’t look up to see the results, because if you treat glioma with the purpose of results it is bound to be an empty one. In life, everyone has painful and difficult times. When there is no way out, the process is more important than the result. Try to make the process perfect! Because a perfect process may abate a little bit of the inner pain.