Many people have the impression that osteoporosis is not associated with death. However, in the opinion of doctors, osteoporosis is a very dangerous disease for the elderly, because after suffering from osteoporosis, the elderly have difficulty moving, shoulder turning pain, and are also particularly prone to fractures due to falls, or even fractures caused by a slight force. Repeated fractures are one of the serious consequences of osteoporosis. Due to the traditional concept and the fear of expensive treatment, many elderly people think that osteoporosis is an unavoidable normal aging and has little impact on their lives, so they are reluctant to treat it even though they know it is a disease, which leads to recurrent fractures and eventually worsens, but increases the burden of medical treatment and affects the quality of life. For example, hip fracture is one of the most serious consequences of osteoporosis fracture, the number of patients with hip fracture caused by osteoporosis is about 1.66 million per year worldwide, and with the aging of the global population, the incidence of hip fracture is expected to increase four times by 2050. After hip fracture, one has to be bedridden for a long time, and the chance of complications such as bed sores, pneumonia, pulmonary embolism and urinary tract infection increases greatly, and the mortality rate is high. Some statistics suggest that 50% of fracture patients need round-the-clock living care, 20% of patients need year-long care, 15% of patients will die due to various complications, and hip fracture due to osteoporosis its morbidity and mortality rate reaches 20% within a year, and about 25% of those who survive for more than a year lose their mobility. In the case of lumbar spine fractures, many elderly people are not diagnosed in time after osteoporotic lumbar spine fractures occur. This is because fractures in the elderly are often low-energy injuries, i.e., they are fractured without significant impact or trauma, mostly from falls or twists on flat ground. In elderly people with severe osteoporosis, the bones are very weak and brittle, and sometimes a small external force such as coughing or constipation can cause a vertebral fracture. Like hip fractures, after a lumbar fracture, many people cannot perform normal activities because of pain, and even need to rest in bed for a long time, which can also cause a series of bed rest complications. Therefore, elderly people with persistent low back pain should be alert to the possibility of a fracture and seek medical attention early, preferably with an MRI, in order to confirm the diagnosis. A proper diet and healthy lifestyle habits can reduce the occurrence of osteoporotic fractures. When it comes to osteoporosis, the vast majority of patients believe that they need to take calcium and vitamin D3 supplements, and this is true. However, calcium tablets are not a substitute for food, and there are adverse reactions to taking more calcium tablets. A healthy and reasonable diet is fundamental, for example, insist on drinking milk and yogurt every day. Dried seafood, shrimp, shrimp skin contains more calcium, the elderly can eat more shrimp skin, because the calcium content of shrimp skin than the general seafood are higher. Vegetables such as beans, pumpkin, eggplant, fungus, capers, amaranth, etc. are also foods with high calcium content. Also pay attention to less smoking, less alcohol (especially beer), less carbonated drinks, tea and coffee. Normally, you can also get more sunlight. Vitamin D3 is important and the best source of intake is sunlight, and it is recommended to have at least 2 times a week with about 10 minutes of sunlight each time. Exercise is especially important for patients with osteoporosis. Some old patients who have had fractures think they need to be sedentary and are always bedridden, but in fact this results in faster bone loss. The elderly should ensure one hour of outdoor exercise every day, the best form of exercise is brisk walking, and older people who are in better health can also choose to run and swim. At the same time with including lifting dumbbells, push-ups, sit-ups, etc., can increase muscle strength and protect bone health. However, for the more serious osteoporosis that has already occurred, relying on methods such as reasonable diet and exercise alone is not enough. Such elderly people need medication in addition to the reasonable diet and good lifestyle habits we mentioned. The new trend in the prevention and treatment of osteoporosis in recent years is that the incidence of fractures must be reduced more effectively, so that not only the bone density should be increased, but also the quality of the bone should be improved and its strength increased. For now, therapeutic drugs are divided into two main categories: one is osteoclast-inhibiting drugs; the other is bone-enabling drugs. The so-called osteoclasts are a class of cells that repeatedly and continuously break down bone tissue for resorption; osteoblasts, which contribute to the construction of bone tissue, are active when they are young and become less active as they age. In the elderly, as they age, osteoblasts begin to be passive and less capable, and although there is also a decrease in osteoclast viability, they still cause more bone loss than bone production, so bone is resorbed and less and less. Different patients have different priorities when choosing these two types of drugs. Menopausal women, because of metabolic changes, have particularly strong osteoclast activity and should use drugs that inhibit osteoclastic ability; while older people, although there is also bone resorption, have a more pronounced decline in osteoclast activity, and if the activity of these cells is not increased and the microdamage to the bone structure is repaired in a timely manner, their bone structure will be full of hollowness, brittle and sparse and will break at the first touch. For such patients, it is important to use bone-enhancing drugs to have a good effect. Evidence-based studies also provide evidence in this regard, suggesting that after 6 months of use, most patients have a significant increase in bone density compared to pre-treatment. In such patients, is it possible to inhibit both osteoclasts and promote osteoblasts in a two-pronged approach? When osteoclasts are inhibited, osteoblasts are also inhibited, and the inhibitory effect will continue for more than one year even if the osteoclasts are discontinued. From a pharmacoeconomic point of view, it is ideal for patients at high risk of fracture to promote osteoblasts first and then switch to osteoclast-inhibiting drugs to maintain and further increase bone mineral density after the drug is finished, in order to ultimately achieve stronger bones and reduce the incidence of fracture. Therefore, the treatment of osteoporosis must differentiate between the application of drugs that stimulate bone formation and those that counteract bone resorption, each patient with osteoporosis must be tested individually, and the treatment plan must be based on the dynamic manifestations of the disease. In general, older osteoporotic patients with slow bone loss are treated with drugs that promote bone formation, while postmenopausal women with rapid bone loss are treated with drugs that inhibit bone resorption. If a patient has a fracture, it means that the patient has severe osteoporosis, and the doctor will help the patient choose a reasonable medication plan according to the degree of fracture and bone transformation after consultation. The only way to avoid another fracture is to improve bone mass and bone strength as soon as possible.