There are many kinds of diseases that cause vague pain in the right upper abdomen, and the common ones are gastric and duodenal diseases, liver and gallbladder diseases, and pleural diseases. 1. Gastric and duodenal diseases: if the patient has heartburn, acid reflux, belching and other symptoms in addition to the symptoms of vague pain in the upper right abdomen, it is likely to be caused by gastric or duodenal diseases. 2. Hepatobiliary diseases: patients may have fever, jaundice, anorexia, nausea and vomiting at the same time, and sometimes the pain will be aggravated after eating greasy food. 3. Pleural diseases: in addition to the right upper abdominal pain, it will be accompanied by coughing, coughing up sputum, and in coughing, or even deep breathing, the pain will be significantly aggravated. It is recommended that patients go to the hospital to complete the relevant examinations, such as abdominal ultrasound, chest CT and blood biochemistry and other tests, to help clarify the cause of the disease, and then under the guidance of the doctor to give symptomatic treatment.