Nowadays, gastroscopy is very popular, so there are many questions about gastric polyps, so here is a brief explanation. Polyps are overgrown tissues that protrude from the mucosal surface into the lumen, and their manifestations, tissue structure and biological properties can vary. 1, gastric polyps can be single or multiple, such as part of the mucosa of the stomach or all the mucosal surface scattered with a large number of polyps of varying sizes called gastric polyposis. Gastric polyps can be divided into two kinds of true and pseudo, true polyps, also known as polypoid adenoma, the nature of the lesion belongs to the tumor hyperplasia, cancer can occur. Pseudo polyps are polyps formed by inflammatory mucosal hyperplasia. 2, the incidence of gastric polyps in asymptomatic people is less than 1%. Gastric polyps can also be divided into two categories: non-neoplastic polyps (including hyperplastic polyps, misshapen polyps, inflammatory polyps, ectopic polyps, etc.) and neoplastic polyps (including flat adenomas, i.e., tubular adenomas and papillary adenomas, i.e., villous adenomas), with the former having a low chance of malignant transformation and the latter having a tendency to malignant transformation. 3, inflammatory polyps do not have the tendency to become malignant; misshapen and ectopic polyps rarely become cancerous. Proliferative (regenerative) polyps are composed of hyperplastic gastric concave epithelium and intrinsic glands with well-differentiated cells, sometimes accompanied by interstitial hyperplasia and disordered smooth muscle bundles, which can generally occur more than one, but rarely occur intestinal, with a low rate of carcinogenesis, only about 1%. However, proliferative polyps may grow up and become localized heterogeneous hyperplasia (adenomatous changes), which may also become malignant. The relationship between gastric polyps and gastric cancer Gastric polyps are not gastric cancer, but some of them have the possibility of malignant transformation and are the precancerous state of gastric cancer. Therefore, patients with gastric polyps should be vigilant, follow up regularly and deal with them in time. Adenomatous polyps are true tumors, accounting for 10%-25% of gastric polyps, and their incidence increases with age. Most of them are flat adenomas without a wide base or with thick and short tissues, less often with tissues or papillae (villous). The histological classification (according to WHO typing) can be divided into tubular, papillary (villous) and mixed tubular-villous types, which are often accompanied by obvious intestinalization and different degrees of heterogeneous hyperplasia. The cancer rate is very high, reaching about 40%. The carcinoma rate is especially high for villous adenomas. Generally, when the diameter of polyps exceeds 2 cm, it is necessary to be alert to malignant transformation. Japanese scholars classify adenomatous polyps as junctional lesions and believe that it is sometimes difficult to determine their benignity or malignancy based on clinical and pathological histological examination alone, and long-term follow-up is required to make a conclusion. Similarly, it should be noted that coexisting gastric cancer is common, therefore, when adenomatous polyp lesions are found, we should look carefully for the coexistence of gastric cancer in other parts of the body, and cases after polyp removal should still be followed up by annual gastroscopy. For most polyps with a tip, the easiest and best treatment is endoscopic removal; for adenomas that cannot be removed endoscopically, the stomach should be cut open for adenomectomy, and more mucosal biopsies should be taken from the adjacent area to observe the presence of heterogeneous hyperplasia or obvious cancer. Patients with familial polyposis and Gardner’s syndrome may also have multiple fundic polyps, gastric adenomas and duodenal adenomas in the stomach, and the incidence of carcinoma in these adenomas is similar to that of disseminated gastric adenomas. Gastric polyps develop at an older age and are often associated with gastric acid deficiency or hypogastric acidity, so they often present with mild pain and discomfort in the upper abdomen, nausea, anorexia, indigestion, weight loss, and diarrhea. Intermittent and persistent bleeding can occur if polyps have erosions and ulcers on their surface. Larger polyps obstructing the pyloric duct or polyp-like sinus mucosa slipping into the duodenum may present with pyloric obstruction symptoms. Fiberoptic endoscopy is extremely helpful in making a definitive diagnosis and determining the presence of cancer. It is generally believed that polyps should be actively treated surgically, depending on the location of the lesion, by partial gastrectomy or total gastrectomy, because of the concern of cancerous changes and the lack of effective drugs for treatment.