Acne is a common condition in adolescent men and women. It mainly appears on the face as white and blackhead acne, papules, pustules, nodules and cysts, and in some cases, even scars. Patients often experience psychiatric symptoms such as anxiety, depression, low self-esteem, and social inhibition. The development of acne is strongly related to androgens. Androgens increase the production of sebum while narrowing the ducts of the sebaceous glands. The increased sebum obstructs the narrowed sebaceous ducts, allowing Propionibacterium acnes to multiply and produce an inflammatory response. The treatment of acne includes the treatment of acne lesions and the treatment of the patient’s psychological problems. Mild acne: topical retinoids or benzoyl peroxide or topical antibiotics. Moderate acne: Oral antibiotics and treatment with anti-androgens in addition to topical medications. Severe acne: Oral isotretinoin with topical medication and treatment with hormones. Be careful not to use topical antibiotics alone. Topical antibiotics need to be combined with retinoids or benzoyl peroxide. Topical medications are not applied only to the affected area but to the whole morbid area; not for a short time but for a long time; more at the beginning and later changed to maintenance; avoid local irritating effects. The use of moisturizers and liquid cleansers can lead to a reduction in inflammatory lesions. The use of scrub cleansing products can dry out the skin and aggravate acne. After topical application of retinoic acid the stratum corneum becomes thin and prone to sunburn. Sun protection is needed and sunscreen is used every day.