Liver cysts are a relatively common type of benign liver lesion in clinical practice. In general, they are often clinically classified into two types: parasitic liver cysts and non-parasitic re-liver cysts. Nonparasitic liver cysts account for the vast majority of clinical liver cysts. What are the common causes of non-parasitic liver cysts? Non-parasitic liver cysts are most commonly associated with congenital liver cysts, also known clinically as true liver cysts. In general, any cause of liver damage may contribute to the development of nonparasitic liver cysts. During the growth and development of the intrahepatic bile duct epithelium of the organism during the embryonic period, there is a possibility of congenital malformation caused by overgrowth of epithelial cells, resulting in the formation of hepatic cysts. Clinical data statistics found that the incidence of non-parasitic liver cysts in women is about four times higher than that in male patients, which is closely related to the high estrogen level in female patients or long-term oral contraceptive use. Some patients suffering from liver abscess or liver trauma and other factors can also cause the development of non-parasitic liver cysts, which shows that the development of non-parasitic liver cysts is the result of multifactorial effects. The vast majority of patients have no obvious clinical symptoms in the early stage of the lesion of liver cysts, and most of them find the liver with cysts occasionally during routine physical examination or examination of other diseases. Some patients if the volume of liver cysts as well as the scope of onset is relatively indistinguishable from patients if the dry cysts are extensive in terms of enterprise as well as convenience, which can cause polycystic liver-like changes in the whole liver, patients with polycystic liver usually choose conservative treatment, and once the patient’s liver is severely damaged, the prognosis is often poor.