Liver cysts are a very common clinical liver lesion and can be classified into congenital and acquired liver cysts depending on the cause of liver cyst formation. Most of the patients with liver cysts are benign lesions, while a very small number of patients with liver cysts can develop cancer and form liver cystic adenocarcinoma. So what are the clinical symptoms of patients with liver cysts? Patients with liver cysts do not have significant liver infection and tumorigenic hypermetabolic injury. Moreover, in some patients with liver cysts, the cysts occur in the liver parenchyma and do not cause compression or irritation symptoms of blood vessels, bile ducts, or intestinal ducts. Therefore, most patients with smaller size liver cysts can have no obvious clinical symptoms. In this case, patients can be advised to review the changes of liver cysts dynamically and no special treatment is needed for the time being. If, during the dynamic review, the patient’s liver cysts increase in size progressively. A liver cyst larger than six centimeters in size can cause compression of the bile ducts and blood vessels in the liver. Patients may experience impairment of liver function and reflux of bile and blood vessels. Patients with severe compression of liver cysts may even develop obstructive jaundice, which may manifest as yellowish staining of the skin and sclera and a tea-like change in the color of the urine. Large hepatic cysts may also compress the intestinal and gastric ducts, and patients may experience nausea, vomiting, acid reflux, and indigestion after eating. In addition, larger hepatic cysts may be accompanied by cholestasis, and patients may experience chills, high fever and other manifestations of cholestasis.