Liver cancer is not sensitive to chemotherapy, and patients with liver cancer often have abnormal liver function, resulting in poor tolerance to chemotherapy. The condition of liver cancer should also be considered. Sometimes chemotherapy is not needed, such as when the patient has reached the middle or late stage of the disease or the patient’s physical condition is poor, and the patient’s family does not really want to use chemotherapy, etc. Moreover, not all cancers need to apply chemical drugs to treat. Therefore, why liver cancer does not use chemotherapy is related to the above factors. There are other ways to deal with liver cancer, such as interventional treatment. In the interventional treatment, besides the embolization agent, it will be combined with embolization agent and chemotherapy drugs together, which is mainly embolization treatment, that is, interventional treatment. Chemotherapeutic drugs are only used as an adjuvant modality, so it may not be specifically and clearly pointed out, and patients may think it is not chemotherapy. Therefore, the above features are the reasons why chemotherapy is not used for liver cancer.