The main clinical manifestations of adrenocortical carcinoma depend on how well the tumor is secreting? Some manifestations are excessive glucocorticoids in the patient’s body, which is medically called Cushing’s Syndrome. Typical manifestations include full-moon face, buffalo back, purple skin lines and high blood pressure. Some patients also show signs of androgen increase, such as female masculinization. Of course, some patients do not show any symptoms because the tumor does not produce too much hormone. As the number of incidental adrenal tumors increases, the number of such patients is gradually increasing. Adrenocortical carcinomas are often very large, with most measuring more than 5 cm in diameter. The weight also ranges from 250 grams to 1000 grams. Therefore, many patients with a thin body type can feel the mass in the upper abdomen.