1, the central nervous system and brain function abnormalities: the vestibular center is to regulate and control the output and control of sensory and motor centers, is the physiological basis for the realization of perceptual integration and kinesthetic integration, the function of the cerebellum is in charge of the coordination and balance of the whole body, and the hippocampus in the limbic system is closely related to activities such as memory and learning, the main function of reticular tissue structure is to evoke attention and activate consciousness activities, brain organism is closely related to brain dysfunction. The neurotransmitters play a very important role in the transmission of information in the central nervous system. 3, Genetic studies have focused on the relationship between X chromosome fragile loci and autism. 4, The occurrence of autism may also be related to viral infections, prenatal abortion, and asphyxia at birth. For example, congenital German measles, in which the mother is infected with the German measles virus early in pregnancy, may lead not only to mental retardation but also to autism. 5.As a metabolic abnormality, fatty deposits in the brain may lead to autism. 6, Other related factors are not listed.