1, caution or even disable nephrotoxic drugs aminoglycoside antibiotics, painkillers, contrast agents, etc. will aggravate kidney damage, patients with one kidney should be cautious with these drugs or even disable them, herbal medicines containing aristolochic acid should be disabled, because aristolochic acid will damage your only kidney, some drugs that need to be excreted or metabolized by the kidneys, although they do not damage the kidneys, but must be excreted or metabolized by the only one kidney, so they need to be properly Reduce the use. 2, actively treat the accompanying diseases that damage the kidney hypertension, diabetes, hyperlipidemia, hyperuricemia, etc. can themselves cause or aggravate kidney damage, patients with one kidney must be actively treated if they suffer from these diseases. Blood sugar, blood lipid and blood uric acid levels should be controlled within the standard, blood pressure should be controlled below 130/80mmHg or even lower and below 125/75mmHg, and if there is proteinuria, it should be reduced to within the normal range as much as possible. 3, the use of drugs to protect the kidney and reduce the burden of the “one kidney” inhibit or block the renin-angiotensin-aldosterone system, such as angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists drugs, can reduce the glomerular hyperperfusion, high pressure and hyperfiltration state of the kidney, reduce the burden of the “one kidney”. “It can be used in small doses and gradually titrated to the maximum dose that can be tolerated, thus achieving the effect of maximum kidney protection. In addition, natural or artificially fermented Cordyceps can reduce the oxygen consumption of kidney tissues, increase the kidney’s tolerance to hypoxia, repair the damaged kidney, long-term use can protect the “one kidney”. 4, adjust the diet and lifestyle appropriate low protein diet, such as protein intake is controlled at 0.8-1.0 grams per kilogram of body weight per day, reduce the intake of phosphorus, phosphorus intake is controlled at 800-1000 mg per day, sodium intake is controlled at 2.4 grams per day or less, which is beneficial to your The protection of the “one kidney”. Proper activity or physical exercise, quitting smoking, drinking less alcohol, and reducing weight in obese people are all beneficial to the protection of the “one kidney”.