In clinical work, it is often found that liver cancer occurs mostly in certain groups of people, and these people are called “high-risk group” for liver cancer. So why are people in these groups prone to liver cancer? After years of efforts, scientists have finally analyzed the main causes of liver cancer. Carcinogenic substances Recently, we also found that some people without hepatitis B and C virus infection and cirrhosis of the liver have developed liver cancer. To trace the cause, these people have a history of long-term and large exposure to carcinogenic substances, the most important of which is aflatoxin. There are more than ten kinds of aflatoxin metabolites confirmed in animal experiments, and aflatoxin Bl, the most common one associated with liver cancer, is a highly toxic substance with strong carcinogenic effect. Its carcinogenic intensity is 75 times higher than that of dimethylnitrosamine (a carcinogen), which can induce liver cancer in all animals. Aflatoxin is present in moldy corn, peanuts, etc. Food is seriously contaminated by aflatoxin Bl areas, the incidence of liver cancer, mortality are higher. Therefore, not eating moldy peanuts, corn and doughnuts fried in gutter oil can reduce the occurrence of liver cancer. Drinking water In recent years, with the increasing domestic and industrial pollution, the eutrophication of some water bodies has become more and more obvious, leading to the abnormal reproduction of algae, especially the growth of green cyanobacteria. Green cyanobacteria growing in pond water, house ditch water is a strong carcinogenic plant, green cyanobacteria in microcystin is a strong carcinogenic substances, it has three isomers, the presence of the most common, more content, more toxic. In an epidemiological survey of drinking water in China, it was found that the incidence and mortality rate of liver cancer were high in those who drank pond water or house ditch water polluted by green algae, while the incidence and mortality rate of liver cancer were lower in those who drank deep well water, and the incidence of liver cancer decreased significantly in people who changed to drink deep well water. Of course, in addition to green cyanobacterial toxins that cause liver cancer, pollution of drinking water may also include many other carcinogenic and cancer-promoting substances. Alcohol and tobacco Do not take up the habit of drinking alcohol under the assumption that it will reduce cardiovascular events or prevent certain diseases. It is now widely accepted that the less you drink, the better, and that it is better not to drink at all. Yet there are still people who drink alcohol in excess over a long period of time and it is another major cause of liver damage. There is a clear dose-response relationship between the amount of alcohol and the development of liver cancer, which means that long-term heavy alcohol consumption will lead to a significant increase in the occurrence of liver cancer as well. Can smoking also lead to the development of liver cancer? Recent studies have found that some chemicals in cigarettes, such as nicotine, cocaine, and nitrosamines, are carcinogenic substances that, in addition to directly damaging liver cells, will further damage the liver when combined with alcohol consumption and viral infections. The risk of liver cancer and the mortality rate of liver cancer due to smoking increases with the number of cigarettes smoked. That is, there is a positive correlation between the amount of smoking and the occurrence of liver cancer.