Patients with constipation and bright red blood are first considered to have perianal lesions such as hemorrhoids, anal fissures, and anal fistulas, and anoscopy is recommended. Secondly, it may also be due to peptic ulcer and other lesions. So there are various ways to deal with it, mainly based on the lesion. 1, hemorrhoids: internal hemorrhoids can take Diyu Sophora pill, bleeding more can take Siwu Tang plus Diyu charcoal, or use Kabaclo, vitamin K, etc. You can also use topical hemorrhoid cream, tannic acid ointment, sai muansan, etc. You can use An’s fumigant, potassium permanganate solution or pepper salt water sitz bath. For prolapsed hemorrhoids use a decoction of Chinese herbal medicine with astringent and astringent properties to sit in the bath, such as Wu Bei Zi, Wu Mei, pomegranate peel, etc. For external hemorrhoids, you can take Diosmin, Diyu Sophora Pill or Wu Wei Disinfectant Drink internally. Constipation serving lactulose, polyethylene glycol and other laxatives, external application of four yellow cream, gold cream; 2, anal fissure: you can consume gastrointestinal Shu, castor oil, etc. to treat constipation, as well as potassium permanganate sitz bath, as well as external use of Ma Yinglong musk hemorrhoid ointment, roxithromycin ointment, antibacterial, anti-infection treatment, as well as lidocaine gel can play a role in relieving local pain. In serious cases, anal dilatation, anal excision and anal hanging can be used for treatment; 3. Anal fistula: those with acute infection episodes or systemic infections need to be treated with antibiotics, such as penicillin and azithromycin. In addition, mainly through local fumigation and drug exchange to promote the disappearance of swelling and pain. For those with local redness and pain, topical antibacterial and anti-inflammatory ointments, such as mupirocin ointment and penicillin ointment, can be applied after fumigation. Severe cases require treatment fistulotomy or anal fistulotomy for treatment; 4, peptic ulcer: including gastric ulcer and duodenal ulcer, commonly used drugs including esomeprazole, omeprazole, rabeprazole, etc., mainly because the drug can reduce the damage to the gastrointestinal tract by inhibiting the secretion of gastric acid, to achieve the effect of hemostasis. Vasoconstrictors, such as norepinephrine and posterior pituitary hormone, have the effect of constricting blood vessels, which can reduce bleeding by constricting blood vessels, thus playing a role in hemostasis; 5. Other lesions: such as malignant tumors, arteriovenous malformations and other causes of constipation and bleeding, you can choose surgical excision treatment, with chemotherapy, radiotherapy and targeted therapy if necessary.