The survival rate of giant hepatocellular carcinoma is generally poor, and the average survival period of patients is only about 3-6 months. Hepatocellular carcinoma is a highly malignant clinical tumor. Depending on the size of the tumor, if the tumor is larger than 10-15 cm in diameter, it is called massive liver cancer. Macroscopic liver cancer is prone to serious complications, such as tumor rupture and bleeding, liver failure, etc. Therefore, the prognosis is very poor. Since most of the hepatocellular carcinoma in giant mass has missed surgery and interventional treatment, conservative treatment with targeted drugs or traditional Chinese medicine is considered to reduce the patient’s pain. At the same time, symptomatic treatment, such as pain relief and nutritional support, is given to try to improve the patient’s quality of life and prolong the patient’s survival time.