The main cause of demyelination of the white matter of the brain in the bilateral lateral ventricles is caused by ischemia and hypoxia of the white matter of the brain. The main treatment is that the patient should usually take oral aspirin, or clopidogrel hydrogen sulfate to antiplatelet aggregation. At the same time, if there are high blood lipids and plaque in the neck blood vessels, atorvastatin or resulvastatin should be given to lower the lipids and stabilize the plaque treatment. Patients should usually take oral Chinese medicine that activates blood circulation and resolves blood stasis, such as Ginkgo biloba ketone ester drops, blood slug tablets, vermifuge and snake Tongluo capsule, and blood stasis and pulse granules, to improve blood circulation in the brain, which is important for the treatment of cerebral white matter demyelination changes. Patients should usually prevent the progression of cerebral white matter demyelination lesions by targeting the risk factors of cerebral atherosclerosis. Strict control of blood pressure, blood lipids, blood glucose, hyperhomocysteinemia, and diet must be low salt and low fat diet are needed.