Cancer not only seriously destroys the patient’s body, but also causes serious trauma to the patient’s spirit and psyche. If the patient has been through the storm and is a brave person, he should tell the patient not to be discouraged with this disease and that he is surrounded by his loving family and friends. At the same time, we should encourage the patient to maintain an optimistic attitude, that everyone will find the most suitable treatment for him, and that as long as he believes in science, even advanced cancer will have the joy of living with the word of life. If it is a more closed-minded and sensitive person, try not to bring up more about the illness, mention the symptoms of the disease as little as possible, try to talk about other events to divert the patient’s attention and talk more about optimistic things. Once there are better changes, let the patient notice these changes in time, which will help the patient build up confidence. Overall, patients with advanced liver cancer need friends and family members’ high compassion and responsibility most, and they should try their best to create a warm and harmonious recuperation environment for patients, and try their best to reduce patients’ psychological pressure, which can be directed to patients’ hobbies, accompany, care, help and support patients more, encourage patients to communicate more and participate in social activities more.