As China enters an aging society, the number of elderly people has increased significantly, and the incidence and prevalence of osteoporosis are significantly higher than before, and this trend is expected to continue for a long time. As in many countries around the world, osteoporosis has become a serious social problem, and fractures caused by osteoporosis have become a fatal killer threatening the elderly and one of the four major chronic epidemics along with hypertension, diabetes and dyslipidemia. These four epidemics have several common characteristics: 1. At the time of onset, most patients are asymptomatic, resulting in relatively low rates of consultation, awareness and treatment. Due to the absence of discomfort, even those who are aware of the disease may be negligent in treating it, resulting in missing the best time for treatment. 2. The consequences are all serious, and all have serious endpoint events. For example, hypertension causes stroke; microangiopathy in diabetes causes multiple organ dysfunction; hyperlipidemia causes cardiovascular events; and osteoporosis causes fractures. All these consequences may directly threaten the life of the patient. 3, once the serious lesions are irreversible, seriously affecting the quality of life of patients. 4, there are effective treatment methods: in the early stage of the disease, the occurrence of the disease can be reduced or delayed through lifestyle interventions, and even if it occurs, through standardized treatment, beneficial therapeutic effects can be obtained, for example, after the occurrence of cerebral infarction, blood pressure control, combined with aspirin treatment, can reduce the occurrence of reinfarction; after the occurrence of heart attack combined with statins, aspirin, beta-blockers, ACEI or ARB drugs can reduce the reoccurrence of cardiovascular events; and effective anti-osteoporosis treatment, such as bisphosphonates and strontium salts, can reduce the occurrence of re-fracture. 5, these diseases are not yet completely cured, all need long-term standardized treatment. However, osteoporosis has different characteristics from other chronic epidemics. 1, osteoporosis is a disease that is almost certain to occur as long as a person lives long enough, and with the loss of bone mass, it is basically certain to occur. In addition, many patients and physicians are not sufficiently aware of the dangers of osteoporosis and the benefits of treatment, believing that osteoporosis is a form of physiological aging that cannot be interfered with. 2, Osteoporosis is more often diagnosed after a serious endpoint event has occurred, and in many cases, instantly after an endpoint event, such as a wrist fracture or lumbar compression fracture, the patient and physician may not even realize that the patient has osteoporosis. 3. In several other chronic diseases, patients usually go directly to the specialist, while osteoporosis is distributed in different specialties, such as orthopedics, endocrinology, rheumatology, obstetrics and gynecology, geriatrics, radiology, and oncology doctors are exposed to such patients. In particular, orthopedic surgeons are often the first doctors to see osteoporosis patients and may be the last doctors to see patients, so osteoporosis requires closer cooperation between orthopedic surgeons and osteopathic physicians. 4, unlike several other diseases, secondary factors causing osteoporosis, such as metabolic diseases, endocrine diseases, tumors, etc., account for a higher proportion of the occurrence of osteoporosis, and require careful examination in order not to miss the diagnosis, which poses a higher challenge to the clinical knowledge and awareness of doctors. 5.The prevention of osteoporosis is not only important but also effective, but its best time for prevention is during the growth and development period, which is far from its onset age, so it is easily neglected. 6.The treatment of osteoporosis lacks immediately observable indicators, and the lack of symptoms also makes it difficult for patients to experience the effect of osteoporosis treatment in an intuitive way within a short period of time, and because osteoporosis is age-related and its treatment is lifelong, therefore, patient compliance plays an important role in the effect of osteoporosis treatment, and patient management and education have a very Patient management and education are of great importance in the treatment of osteoporosis. These are the areas where osteoporosis differs from other chronic epidemics. In conclusion, osteoporosis is a killer that, like other chronic epidemics, poses a great threat to human health, but it has its own unique style. Only if we really pay attention to it and strengthen the cooperation of the whole society, especially the government, doctors and patients, can we really remove its threat.