Normal blood uric acid concentration Male: 150-350 umol/L Female: 100-300 umol/L Diagnostic criteria for Hyperuricemia (HUA) Male >420umol/l (7mg/dl) Female >357umol/l (6mg/dl) (fasting blood uric acid level on two different days under normal purine diet) How to avoid hyperuricemia Lifestyle improvement; active treatment of metabolic risk factors associated with elevated blood uric acid; avoidance of drugs that elevate blood uric acid; use of drugs that lower blood uric acid; dietary control; low purine diet (especially avoid animal offal, seafood!) Avoid alcoholic beverages (especially avoid beer!) Drink more water: it is best to maintain a daily fluid intake of 1.5-2 liters or more, to increase urine output of 2000-2500 ml per day, and to increase uric acid excretion; exercise and weight control.