I. The following cases can be considered for artificial insemination by husband: 1. Infertility due to less sperm, weak sperm, abnormal liquefaction, sexual dysfunction and genital malformation in the male partner. Infertility due to cervical factors of the female partner; if the female partner has had physiotherapy or surgery on the cervix in the past, it can lead to infertility by affecting the cervical mucus. 2. Infertility due to abnormalities of the reproductive tract and psychological factors such as inability to have sexual intercourse. 3.Unexplained infertility and immune infertility. 2. The following cases can be considered for artificial insemination by sperm donation: 1. irreversible azoospermia. 2. The male partner or the family has serious hereditary diseases that are not suitable for fertility. Those who refuse to perform PGD. Severe oligospermia, weak spermia and teratospermia; failed vasectomy; ejaculation disorder and refusal or inability to perform epididymal or testicular puncture to obtain sperm can also be considered for donor insemination for conception, but patients can also have their own blood-related offspring through intracytoplasmic single sperm microinjection, and if the patient couple insists on giving up this right, donor insemination technique can be used for conception.