The duration of life on targeted drugs for advanced lung cancer cannot be specified and needs to be evaluated in the context of patient’s specific situation. Targeted therapy for lung cancer mainly uses targeted drugs to enter the body to specifically bind with cancer-causing sites to kill cancer cells. Before applying targeted drugs to patients with advanced lung cancer, genetic testing should be done to determine whether they can be applied. If they are not applicable, but continue to apply targeted drugs, not only will they be ineffective, but also will cause side effects. If it is suitable to apply targeted drugs, it can extend the survival period of advanced lung cancer patients by half year to one year, but the specific situation varies from person to person. In addition, patients need to pay attention that they must be examined before applying targeted drug therapy, and CT or MRI should be performed regularly after application to clarify the treatment.