Interventional treatment of ovarian cancer and other gynecologic tumors

  With the rapid development of medical technology level and the increasing awareness of women pursuing quality of life, life and quality of life together are getting more and more attention in the field of gynecological malignant tumors.  Gynecological tumors are common diseases that endanger women’s health. Common benign gynecological tumors include uterine fibroids, endometriosis, benign ovarian tumors, etc.; malignant tumors with higher incidence include cervical cancer, ovarian cancer and endometrial cancer. Since the uterus and ovaries are located deep in the pelvic cavity and cannot be seen or touched directly, many gynecological tumors are already in the middle and late stages when they are found, and patients have heavy symptoms such as abdominal mass, abdominal pain, irregular vaginal bleeding, and extensive metastases in the pelvis and systemic organs, so they often lose the opportunity of surgery. Even for the few patients who can be treated surgically, not only do they have to undergo total uterine and adnexal removal and extensive lymph node dissection in the pelvis, but they also need multiple courses of radiotherapy and chemotherapy after surgery. The side effects of these treatments have seriously reduced the quality of life of patients.  In recent years, the development of interventional therapy, which uses advanced instruments to reach the tumor site directly for diagnosis and treatment, has gained rapid momentum. Through more than 40 years of in-depth basic and clinical research, interventional therapy has been applied to various types of gynecological malignant tumors and has become an effective supplement to traditional treatment methods.  I. Interventional embolization therapy Interventional embolization therapy is to treat gynecologic malignant tumors by suspending the blood supply of tumors and causing ischemic necrosis of tumor tissues, which can soften the tumor surrounding tissues after embolization, reduce local infection and appear surrounding edema, make the tumor easy to be peeled off during surgery, reduce intraoperative bleeding, clear surgical field, and control the spread and metastasis of cancer cells during surgery; it can also shrink the tumor lesions, reduce It can also shrink the tumor lesion, reduce the complications of surgery, or make the patients who have lost the chance of surgery in the middle and late stage get the chance of surgery and create conditions for the follow-up treatment. For patients with advanced malignant tumors and postoperative recurrence, interventional therapy as palliative treatment has the advantages of minimally invasive and repeatable, which can reduce patients’ pain, improve their survival quality and prolong their survival time.  II. Interventional chemotherapy In addition, interventional chemotherapy is also an essential and important method for the treatment of gynecological malignant tumors. The higher the local drug concentration of tumor, the longer the contact time between the drug and tumor cells, the better the anti-cancer effect of the drug. However, conventional systemic intravenous drug administration, the drug concentration in the lesion area cannot reach a certain high concentration, so the efficacy is limited and the toxic side effects are large. Therefore, by using interventional intubation, the catheter is super-selected into the blood supply artery of tumor, and the one-time high-dose infusion of chemotherapeutic drug impact treatment can multiply the local drug concentration of tumor and improve the anti-cancer effect of drugs.   Interventional methods for benign gynecological tumors For benign gynecological tumors, such as uterine fibroids with high incidence, embolization of the tumor blood supply artery can be used to achieve the purpose of making the tumor ischemic, necrotic, absorbing and disappearing, especially for patients who wish to preserve the uterus, not only the clinical symptoms are obviously relieved, but also various endocrine functions of women can be preserved to the greatest extent. In addition, argon helium ultra-low temperature cryopreservation and ultrasound, radiation and endoscopy-guided interventional techniques have been widely used in the diagnosis and treatment of gynecologic tumors. The application of these interventional techniques will play an irreplaceable role in improving the life treatment of female patients.