Urine protein a + cannot represent nephritis. Clinically there are many diseases that can cause urine protein a +. The most common physiological transient proteinuria, such as eating large amounts of protein recently or strenuous exercise, congenital developmental abnormalities, such as the Nutcracker phenomenon. Another pathological condition requiring treatment is most commonly nephritis, pyelonephritis, nephrotic syndrome, amyloidosis, myelomeningocele kidney disease and diabetic nephropathy. If there is a + urine protein, it is recommended that further 24-hour urine protein quantification and ion renal function, liver function, nail function and other related tests be performed to clarify the etiology, and the most commonly applied urine protein-lowering drugs are ACEI and ARB class.