Lymphoma is a common malignant tumor, and its early symptoms are not easy to be found, so it is easy to miss the best treatment time; some people think that lymphoma is linked with “death” in our impression, and once suffering from this disease, the patients themselves may not hold any hope, so it is quite important to know what are the symptoms of lymphoma in early stage. Therefore, it is very important to know what are the early symptoms of lymphoma. Early Symptoms of Lymphoma 1. Fever The fever of lymphoma is irregular, and it can be persistently high. It can be intermittent low fever or intermittent fever, the latter is seen in about 1/6 of Hodgkin’s disease patients, and the early fever of Hodgkin’s disease accounts for about 30%~50%, but non-Hodgkin’s lymphoma usually develops fever when the lesion is more extensive. The disease can be characterized by profuse sweating as the warmth subsides. If there are more than two times in a month with fever, sweating, cough and other cold-like symptoms, and the temperature is more than 38℃ when the fever is measured, we should first consider investigating lymphoma. Itchy skin This is a more specific symptom of early lymphoma. It is a kind of skin disease without primary rash but with itching. Pruritus belongs to neuropsychiatric skin disease, which is a kind of skin neurosis. Focal itching occurs in areas of lymphatic drainage from the lesion, and generalized itching occurs mostly in cases with lesions in the mediastinum or abdomen. Itching disappears when part of the cancer is removed and reappears before the tumor recurs. It can be said that the appearance of itching is also the signal of tumor recurrence. Alcoholic pain Some patients with Hodgkin’s disease have pain in lymph nodes or bones after drinking alcohol, which is earlier than other symptoms and X-ray manifestations and has certain diagnostic significance. If the pain occurs in the position of the femoral head, it may be misdiagnosed as alcoholic femoral head necrosis, lumbar numbness, aching symptoms, the pain may be severe or vague, these are blood circulation disorders, stimulate the nerves, the patient can feel the lumbar pain. 4, gastrointestinal tract Lymphoid tissue outside the lymph nodes occurring in malignant lymphatic lesions are most often seen in the gastrointestinal tract, clinical manifestations of loss of appetite, abdominal pain and diarrhea, abdominal mass, intestinal obstruction and bleeding. The site of invasion is mainly the small intestine, more than half of which is the ileum, followed by the stomach, while the large intestine and esophagus are rarely involved. Primary small intestinal tumors are mostly non-Hodgkin’s lymphoma, which can be episodic abdominal cramps, active mass, progressive incomplete obstruction or malabsorption, steatorrhea as the main clinical manifestations. 5.Bone Part of lymphoma patients will have cancer involving bones, with thoracolumbar vertebrae most often involved, femur, ribs, pelvis and skull secondly, manifesting local bone pain, pressure pain, pathological fracture, bone tumor and secondary nerve compression. Diffuse large cell or histiocytic type can originate in the skeleton, patients are younger, mostly in the long bones, mainly osteolytic. If skeletal lesions are formed, there may be spread of systemic lymph nodes and internal organs sooner or later, but it may also be confined to the skeletal system indefinitely. Besides the above mentioned damages, there are specific skin damages such as granulomas, lumps and subcutaneous nodules; kidney involvement may cause serious renal failure; enlarged lymph nodes in the whole body; mainly in the neck, followed by axillary and inguinal lymph nodes, and mediastinal lymph nodes may be involved in the late stage.