Lymphoma is known as malignant lymphoma in clinical practice. Patients with advanced malignant lymphoma usually have no special signs one week before death, but some common symptoms are likely to appear due to the gradual failure of various organs in advanced malignant lymphoma, mainly fever, alcoholic pain, itchy skin, night sweats, emaciation, weakness, gastrointestinal symptoms, etc. 1. This may lead to dysfunction of the thermoregulatory center, which may lead to persistent hyperthermia and intermittent fever. 2. Alcoholic pain: Some patients with advanced malignant lymphoma may experience pain at the lesion site for a period of time after drinking alcohol. 3. Itchy skin: One week before death, most of the tumor cells of patients with malignant lymphoma have spread to all parts of the body, and the skin of the enlarged lymph nodes may become itchy. If the tumor cells invade the thoracic cavity, abdominal cavity and other parts of the body, the symptoms of general itching may also appear; 4. Night sweats: one week before death, patients with malignant lymphoma may have night sweats during sleep or after sleep; 5. Lymph node fusion and other manifestations; 6. Wasting and weakness: Patients with malignant lymphoma may have unexplained wasting and weakness in the late stage; 7. Gastrointestinal symptoms: Patients with malignant lymphoma may show symptoms related to the gastrointestinal tract one week before death if the cancer cells have metastasized to the gastrointestinal tract, such as loss of appetite, difficulty in swallowing, abdominal pain, diarrhea, bleeding from intestinal obstruction and other manifestations; 8. Patients have a greenish-gray face one week before death, and often show insomnia, chest tightness, anemia, jaundice, liver and spleen enlargement, hoarseness, coma, etc.