Transplant success in patients with aplastic anemia

The success rate of bone marrow transplantation in patients with aplastic anemia is statistically shown to be in the range of 60% to 70%. The success rate of bone marrow transplantation is related to the method of transplantation and factors such as infection and immune rejection, so the success rate and risk of transplantation vary from patient to patient. 1. When the patient undergoes bone marrow transplantation, if the HLA antigen match between the bone marrow donor and the patient is relatively high, in this case, the rejection reaction is relatively weak, and the postoperative effect is usually better, with a success rate of more than 90%, if the HLA antigen match between the bone marrow donor and the patient belongs to hemizygous match, the success rate of the transplantation is usually about 50%. 2. In addition, postoperative infection should be prevented as much as possible, because the immune system function of patients who have just undergone bone marrow transplantation has not yet been rebuilt, and their resistance to bacteria or viruses is relatively weak, so if an infection occurs, it may have an impact on the bone marrow transplantation. Medications include levofloxacin, etc. In addition, if serious complications such as graft-versus-host disease occur after transplantation, the success rate of bone marrow transplantation will also be reduced. Specific treatment should be directed by a physician.