Drug-induced gingival hyperplasia is a common clinical periodontal disease. Nifedipine, a 1st generation calcium antagonist, is effective in treating intractable hypertension and primary hypertension, and its side effects can trigger gingival tissue overgrowth and gingival volume increase. Drug-induced gingival hyperplasia mainly involves the gingival papillae and labial-lingual attached gingiva, which are painless at onset and become candida-like. As the disease progresses, the hyperplastic gingival papillae and the hyperplastic marginal gingiva unite into patches and continue to grow. In the absence of inflammation, the gingiva is pale pink and tough, and there is no bleeding on probing. However, areas of hyperplasia are often associated with varying degrees of inflammation due to plaque buildup. In this case, the hyperplastic gingiva is large lobulated, flabby, and has a pronounced bleeding tendency, mostly involving the maxillary and mandibular anterior teeth, and rarely reported to occur in edentulous areas. Patients with hypertension taking nifedipine for a long time should pay special attention to oral hygiene to prevent gingival hyperplasia that can be caused by nifedipine! If gingival hyperplasia has already occurred, the first step is to do basic periodontal treatment, systematic scaling to eradicate tartar, followed by attention to oral hygiene, thorough brushing and flossing. Regular review. If you can change your medication, it is recommended that you consider changing your medication. In fact, you can change many varieties of medication, and the specifics suggest that you consult a cardiologist.