Gingival hyperplasia on nifedipine, replacement of antihypertensive medication with a non-calcium antagonist. Nifedipine is a dihydropyridine calcium antagonist used in the treatment of various types of hypertension. Oral nifedipine can cause gingival hyperplasia among other adverse effects, in which case it is necessary to change non-calcium antagonist antihypertensive drugs such as valsartan, benadryl, metoprolol and other antihypertensive drugs under the supervision of a physician. Other adverse effects of the drug are palpitations (rapid heartbeat, often accompanied by panic), sinus tachycardia, dry mouth, sweating, headache. Contraindications are mainly for those who are allergic to nifedipine. Oral antihypertensive drugs when adverse reactions need to promptly consult the doctor, under the guidance of the physician to replace the drug, do not replace their own to avoid adverse reactions.