Taking antihypertensive drugs gingival hyperplasia can be replaced with drugs such as metoprolol and valsartan. Calcium antagonists such as amlodipine, nifedipine, etc. may cause gingival hyperplasia when taken for a long period of time, and the symptoms can be gradually relieved after stopping the drug, which will not lead to permanent gingival hyperplasia. For patients with gingival hyperplasia on calcium antagonists, they can be replaced with other antihypertensive drugs with other mechanisms of action, such as angiotensin II receptor antagonist valsartan, ali-sartan and so on. They can also be replaced with the beta receptor antagonists metoprolol and atenolol, or oral diuretics such as indapamide, none of which have the adverse effect of gingival hyperplasia. In the process of taking calcium antagonists, attention should be paid to strengthening the monitoring of adverse reactions, and patients with gingival hyperplasia should go to the hospital in time, and adjust the treatment program under the guidance of physicians.