Pharmacologically, there is no mutual effect of taking Azithromycin and drinking alcohol. But it is not recommended to drink alcohol while taking the drug and be responsible for your own life. There are some drugs that can affect the metabolism of alcohol and aggravate the intoxication reaction, there will be panic, palpitations, dizziness, headache, headache, serious and even life-threatening, although clinically rare, but indeed seen. Drugs that react with alcohol are generally common anti-inflammatory drugs, such as cefixime and cefadroxil of the cephalosporin class; metronidazole and ornidazole. There are some hypoglycemic drugs that can react with alcohol, such as glibenclamide. Some anticoagulant drugs, like warfarin, can also react with alcohol, so do not drink alcohol while taking medication.