Many patients in this case have a sudden onset of the disease and find themselves cold and even shivering, followed by a high fever, or what we think of as a “double whammy”. For people who are weak, malnourished, or have a small child, they may not have a fever, but they may have a lower than normal body temperature. Of course, some patients may also appear to be very depressed or feel emotionally irritable, or even have a white face and a fast breathing and heart rate. Skin lesions After the disease, children may have skin rashes such as petechiae, red spots, and scarlet, especially on the feet, hands, and inside the mouth. Gastrointestinal symptoms After the disease, there is often vomiting, diarrhea, stomach pain, and even vomiting blood, diarrhea out of blood phenomenon. IV. Out of joint symptoms Some patients may find pain in joints such as hands and feet, and even find it difficult to walk. V. Hepatosplenomegaly symptoms This should be said to be more frequent in children, parents can pay close attention to it. Sixth, other symptoms Various kinds of mental confusion, drowsiness, sudden coma, and oliguria may be caused by the disease. The primary lesions are often skin boils and carbuncles or wound infections, and a few are hospital-acquired infections with poor body resistance, and the germs in the blood are mostly from the respiratory tract. The presence of petechiae on the conjunctiva is of great importance. Migratory damage can occur in about 2/3 of patients, most commonly multiple pulmonary infiltrates, abscesses and pleurisy, followed by suppurative meningitis, renal abscesses, hepatic abscesses, endocarditis, osteomyelitis and subcutaneous abscesses. Infectious shock is less common. 2. Sepsis of Staphylococcus epitheliae Most commonly seen in hospital infections, when patients receive broad-spectrum antibiotic therapy, the bacteria are prone to form drug-resistant strains (methicillin-resistant strains), the number of this bacteria in the respiratory tract and intestinal tract increased significantly, which can lead to systemic infection, but also commonly after interventional treatment, such as artificial joints, artificial valves, pacemakers and various catheters left in the case. Enterococci sepsis Enterococci are opportunistic infections, usually mainly in the intestinal tract and urinary system, its incidence has increased in the past 30 years, clinically manifested as urinary tract infection and endocarditis is most common, in addition to meningitis, osteomyelitis, pneumonia, enteritis and skin and soft tissue infections.