High blood glucose after heart transplantation can be treated with relevant medications, such as oral hypoglycemic drugs and insulin injections, while paying attention to diet control. The increase of blood glucose after heart transplantation may be caused by postoperative stress hyperglycemia, if the increase of blood glucose is more obvious, it can be temporarily treated with drugs to lower blood glucose, and insulin is usually used to control blood glucose. Elevated blood sugar after surgery, may also be suffering from diabetes mellitus, can be further clarified by perfect glucose tolerance, glycated hemoglobin and other tests. You can take oral hypoglycemic drugs, such as metformin, acarbose, or subcutaneous insulin treatment. At the same time, attention should be paid to diet control, regular review. It is recommended to consult a doctor in time, and the specific medication should be under the guidance of the doctor.