Premature infants are a special group of newborns, born at a small gestational age, with low weight and immature systems and organs, especially since many of them survive the life-saving techniques of the neonatal intensive care unit. Therefore, as high-risk infants, preterm infants require regular follow-up in outpatient clinics to monitor development for early detection of problems. At the same time, due to the plasticity of preterm infants’ brain during the critical period of development, creating a good nurturing environment and carrying out comprehensive early interventions as the first responsible parent in the family where the child is raised on a daily basis can promote organ maturation, physical growth and brain development, thus improving the quality of survival and the prognosis of preterm infants. Early intervention is the implementation of planned, organized, and purposeful environment-rich educational activities for infants and toddlers in advance, before abnormal problems occur, to promote the potential of high-risk newborns according to the laws of infant and toddler intellectual and physical development. Early intervention for preterm infants can begin at 40w of gestational age because the less mature the brain, the faster the growth and development and the more plastic it is. Early intervention includes intelligent training and physical training, such as auditory stimulation, visual stimulation, tactile stimulation, balance training, and gross and fine motor training. For example, hearing can be trained from birth by using “language first”, i.e., using meaningful language to describe the infant’s behavior in the daily parenting process; visual stimulation by moving brightly colored objects for the infant to see or by showing the baby the parent’s affectionate face; passive limb flexion, touch and massage, and grasping Tactile training through passive flexion, touch and massage, and grasping stimulation. The Health Education Clinic of the Department of Child Health offers a series of courses on early development of preterm infants to educate parents in an organized and purposeful way, so that parents can obtain authoritative and systematic information on parenting, become comfortable with various problems in the process of parenting, reduce unnecessary abnormalities in the process of growth of the baby, make parents more comfortable in the process of parenting and promote the overall healthy growth of the baby. Early family intervention is not only applicable to some high-risk babies such as premature babies, but also to full-term healthy babies.