Characteristics of hypertension caused by adrenal disease Hypertension caused by adrenal disease is one kind of secondary hypertension, mainly including primary aldosteronism, pheochromocytoma and cortisolism. Patients with aldosteronism may have intractable hypertension with hypokalemia, patients with pheochromocytoma may have high and low blood pressure, and patients with cortisolism may be accompanied by centripetal obesity and other manifestations in addition to hypertension. 1. Primary aldosteronism: due to adrenal cortex hyperplasia or tumor secreting too much aldosterone, it can cause intractable hypertension, and the blood pressure is usually difficult to control, and it is often accompanied by hypokalemia symptoms such as muscle weakness and periodic paralysis. 2. Pheochromocytoma: due to intermittent or persistent release of excessive adrenaline and dopamine from adrenal gland tumor, the patient’s blood pressure will be high and low, and it can be reduced to normal on its own, accompanied by tachycardia, headache, sweating, and pallor. 3. Cortisolism: also called Cushing’s syndrome, due to the excessive secretion of adrenocorticotropic hormone caused by excessive glucocorticoids, the patient may appear hypertension, centripetal obesity, full-moon face, purple lines on the skin, increased blood glucose and other clinical manifestations. The characteristics of adrenal-induced hypertension are different depending on the cause of the disease, and patients should go to the specialist in time for treatment for the cause of the disease.