Lung cancer with pleural effusion belongs to wet lung cancer, which is a common complication in the late stage of lung cancer, causing chest tightness and difficulty in breathing, directly affecting the survival period and quality of life of patients. Untreated patients mostly die within 1-6 months (average 2 months) after the appearance of pleural effusion. The use of traditional methods to repeatedly pump out the effusion will only cause the patient to lose a large amount of protein, electrolytes and other components, and the survival period is usually 3-4 months, which has long troubled patients and medical workers. Body cavity circulation thermal perfusion therapy equipment, the machine uses the extracorporeal circulation pump to introduce it into the body cavity or blood vessels, and continuous circulation, through the temperature measurement system to monitor the temperature of the outlet, inlet and body cavity, to ensure that the temperature in the body cavity is maintained at 42℃-45℃ for a certain period of time, so as to cause apoptosis of tumor cells. Thermal perfusion chemotherapy is a new therapy that combines the application of chemotherapy and thermal therapy to treat tumors. Its principle is to use physical energy to heat chemotherapeutic drugs with good thermal effect and infuse them into the tumor site to raise the temperature of tumor tissues to the effective treatment temperature and maintain it for a certain period of time, so as to achieve the therapeutic purpose of causing apoptosis of tumor cells without damaging normal tissues by using the difference of temperature tolerance ability between normal tissues and tumor cells. Thermal perfusion chemotherapy makes the organic complementary effect between thermal therapy and chemotherapy perfusion drugs, and increases the sensitivity of patients to chemotherapy. It can kill malignant tumor cells more effectively, improve patients’ survival quality and prolong their lives, and at the same time reduce the side effects caused by radiotherapy and chemotherapy, thus it is called “green therapy” by the international medical community. Indications: 1. Thoracic tumors: wet lung cancer, pleural mesothelioma, cancerous pleural effusion. 2.Cancerous peritoneal effusion. 3.Thoracoabdominal metastasis caused by breast cancer and ovarian cancer. 4.Thoracoabdominal cavity infiltration by malignant lymphoma. 5.Pericardial effusion caused by various malignant diseases . 6.Remedial treatment for incomplete resection of thoracic and abdominal tumors during surgery and prevention of postoperative tumor implantation and metastasis.