Chronic bronchitis has a long and slow onset. When an acute attack occurs, the patient’s main symptoms are a new cough, coughing and wheezing, or a significant increase in the original symptoms, such as a significant increase in sputum volume, yellowish consistency, shortness of breath, or even fever. A small number of patients may have blood in the sputum, and the sputum may be more abundant in the morning. In the treatment of acute exacerbation, infection control is the first priority, and antibacterial drugs can be selected empirically according to the common pathogenic bacteria in the patient’s location, including levofloxacin, roxithromycin, amoxicillin, cefuroxime, etc., which are often used clinically. Theophylline or nebulized inhalation can be used to improve the symptoms.