Liver cancer is the king of cancers and has a high death rate. Most of the patients have the foundation of hepatitis and cirrhosis, which makes treatment difficult. The Department of Hepatology of Zhucheng Hospital of Traditional Chinese Medicine implements the diagnosis and treatment standard of liver cancer of the Ministry of Health and adopts multidisciplinary integrated treatment methods, so that most patients can obtain satisfactory control effect. The following therapeutic measures applied jointly are the most reasonable ways of hepatocellular carcinoma treatment at present, which can relieve patients’ pain and prolong their lives to the maximum extent. 1. Hepatic artery chemoembolization, which can maintain local high concentration of chemotherapeutic drugs and block the blood supply to the lesion, causing ischemia and necrosis of the mass, with less impact on the surrounding normal liver tissues and the whole body. It is the most effective treatment method preferred for middle and late stage liver cancer. 2.Local ablation, which is guided by imaging technologies such as US, CT and MRI, to target and locate the tumor and kill the tumor tissue directly by physical or chemical methods through percutaneous route. It includes radiofrequency, microwave ablation and anhydrous ethanol injection, etc. It is minimally invasive, safe, simple and easy to perform for many times. 3.Systematic chemotherapy, such as intravenous injection of arsenic trioxide, can inhibit the growth of micro lesions and enhance the therapeutic effect. 4.Therapy with Chinese medicine can relieve abdominal distension and cancer pain, enhance physical fitness, and strive for the highest therapeutic effect.