High cardiac enzymes in children may be caused by physiological factors such as excessive exercise and lack of sleep, or there may be pathological factors, commonly seen in cardiac muscle injury, muscle injury, cranio-cerebral injury, etc. It is recommended to analyze and judge the results in conjunction with other tests to clarify the cause. I. Physiological factors: Cardiac enzymes are normal substances that exist in human muscle tissue. As there is no reference standard for cardiac enzyme test results only for small children, most of them refer to adult standards, so if children have mildly increased cardiac enzyme and no other clinical symptoms, it is mostly considered as physiological factors, such as excessive exercise and lack of sleep, which can cause transient cardiac enzyme increase in children, and no special treatment is needed, as long as good rest can be maintained. Pathological factors: 1, myocardial injury: when there is myocardial injury, such as viral myocarditis, myocardial enzyme indicators will appear significantly higher, especially creatine kinase and creatine kinase isoenzyme, including troponin will also appear significantly higher. Children may have diarrhea, abdominal pain, vomiting, fever, excessive sweating, pallor, weakness, shortness of breath, and other symptoms. In this case, it is recommended to observe the clinical symptoms of small children, keep them in bed as much as possible, carry out antiviral treatment and myocardial nutrition under the guidance of a doctor, and pay attention to regular review. 2. muscle injury: muscle is rich in creatine kinase and creatine kinase isoenzyme, and when muscle tissue is damaged or strained, creatine kinase and isoenzyme will be released into the blood, which will lead to elevated creatine kinase. When muscle injury occurs, you can limit the activity, oral or injectable antipyretic analgesic and combined with related physical therapy, more commonly used infrared radiation, etc.; 3, cranio-cerebral injury: common cranio-cerebral injury are traumatic brain injury, cerebral hemorrhage, encephalitis, etc., can appear creatine kinase elevation. This is because creatine kinase also exists in the brain tissue, when the brain tissue damage, creatine kinase is released into the blood, causing an increase in the value. When a cranio-cerebral injury occurs, it can be characterized by unstable breathing, pulse, blood pressure, and heartbeat, as well as headache, dizziness, and increased intracranial pressure. It is recommended to promptly seek medical attention for cranial CT examination to clarify the cause and treatment.