Cerebral infarction is the disease with the highest rate of disability and the second highest rate of death, which brings a huge burden to patients’ personal and family and greatly affects the quality of life. In the following series, I will introduce the first aid of cerebral infarction in layman’s language, hoping to bring a little help to the patients and their families who have the chance. Ma Gaoting, Department of Neurology, Shandong Qianfo Mountain Hospital Time is the brain, and when a brain infarction occurs, for every minute of delay, about 1.9 million brain cells die. Therefore, once an acute cerebral infarction occurs, it is recommended to immediately go to the nearest hospital with “thrombolysis or thrombus retrieval” capability to “reopen” the blood vessel through emergency thrombolysis or mechanical thrombus retrieval within 3.5-4.5 hours or longer. If this time period is missed, minor cases may recover, but serious cases can only be described as “the water cannot be recovered, the situation has already gone, the wood has become a boat” and so on, and even a miracle doctor can do nothing. Then, how to determine acute cerebral infarction becomes the primary problem. First of all, most patients with cerebral infarction have high blood pressure, diabetes, hyperlipidemia, smoking, drinking, family genetics and other high-risk factors, and some patients may also have coronary heart disease and other atherosclerosis-related diseases in combination. Therefore, no matter the patient himself or his family, there should be such a string in his heart: the probability of having a brain infarction is higher than that of ordinary people! Secondly, cerebral infarction is usually acute, and the sudden appearance of symptoms can catch people off guard. The symptoms may resolve on their own within a few minutes, so don’t take any chances, this is a “transient ischemic attack”, if not handled properly, there is a great chance to progress to cerebral infarction. Finally, cerebral infarction has some special symptoms, broadly speaking: overall: dizziness, nausea, vomiting, fainting, unconsciousness, sleepiness, abnormal mental behavior, etc. Head and face: slanted eyes and mouth, slurred speech, difficulty in opening mouth, forgetting words, difficulty in describing, staring with both eyes, tongue extension, choking and coughing, difficulty in swallowing, etc. Limb: weakness, numbness or even complete paralysis on one side. Patients with risk factors should seek regular medical care and active drug and lifestyle interventions to prevent cerebral infarction. Once an acute cerebral infarction occurs, it should be judged and sent to the doctor as early as possible to give the doctor and the patient a chance to save their lives. This article is published with permission from Dr. Gao-Ting Ma.