What are the blood indicators of leukemia?

Features of leukemia blood indicators: 1. Leukocytes: the count can be as high as 30×10/L or as low as (0.2~0.3)×10/L (hypoproliferative leukemia).

The white blood cell count is usually low in the early stages of acute leukemia and mostly high in the late stages. When the total white blood cell count is particularly high or low, the disease is often severe and the treatment is difficult and less effective. The presence of acute leukemia cells in the peripheral blood is an important basis for the diagnosis of acute leukemia. Acute leukemia is mainly characterized by primitive and promyelocytic (naive) cells. The diagnosis is not difficult when the total leukocyte count is high, but when the leukocytes are low, leukemic cells are often found only after a concentrated smear or up to the end of a blood smear. The blood picture of promyelocytic leukemia or hypoproliferative leukemia is often totocytopenic.

Chronic granulocytic leukemia: The leukocyte count is markedly increased in the chronic phase, higher than 20×10/L in the early stages and up to 100×10/L in the late stages. Neutrophils are seen in all stages, with predominantly neutrophils, late neutrophils, and rod-shaped nuclei; eosinophils and basophils are increased; anemia may be present; and platelets are normal or increased in the early stages and gradually decrease in the late stages.

Chronic lymphocytic leukemia blood work: peripheral blood B lymphocytes ≥5×10/L and persistent for at least 3 months. 2. Red blood cells and hemoglobin: generally show orthocytic, normochromic anemia, and sometimes juvenile red blood cells are seen in blood films. Reticulocytes are often reduced, but in a few cases there can be a mild increase. 3. Platelets: The number of platelets can be normal or mildly reduced in the early stages of leukemia, and in the mid- to late-stage, there can be a significant reduction to less than 10 × 10/L, platelets of unequal size and abnormal shape, with giant platelets, abnormal platelet factor III and coagulation function.